Methyl Cellulose (MC) thiab hydroxypropylulose (HOLMC) yog ob qho tib si cellulose derivicals thiab tau siv dav hauv cov khoom noj, khoom siv tsev thiab lwm thaj teb. Txawm hais tias lawv yog ob qho tib si los ntawm ntuj cellulose thiab muaj kev ua haujlwm zoo sib xws hauv cov ntawv thov tshuaj, cov khoom siv lub cev, daim ntawv thov cov yam ntxwv thiab cov yam ntxwv ua haujlwm.
1. Cov qauv tshuaj lom neeg thiab cov txheej txheem npaj
Methyl Cellulose (MC): Methyl Cellulose yog tsim los ntawm kev hloov ib pawg lossis tag nrho cov pab pawg hydroxyl (-o cellulose nrog cov pab pawg methoxy (-ochiv). Tshwj xeeb, cov pab pawg hydroxyl hauv cellulose muaj kev ntxhov siab nrog cov tshuaj tiv thaiv methylating (xws li methyl chloride) nyob rau hauv alkaline tej yam kev mob los tsim methylcellose. Vim muaj kev hloov pauv sib txawv, mc tuaj yeem sib txawv solubility thiab viscosity.
HydroxyPropyyl methylcellose (HPMC yog qhov ntxiv hloov kho ntawm MC, tsis yog tsuas yog cov pab pawg me me, tab sis kuj yog ib feem ntawm cov xov xwm hydroxy, tab sis kuj yog ib feem ntawm cov xov xwm hydecle, tab sis kuj yog ib feem ntawm cov xov xwm hydecule tau hloov nrog cov pab pawg hydroxypropule) hydroxy. Kev npaj ntawm HPMC koom nrog ob-kauj ruam kev tawm tsam: thawj zaug methylation cov tshuaj tiv thaiv thiab tom qab ntawd ib qho tshuaj tiv thaiv hydroxyprropation. Vim tias qhov no hloov chaw, cov khoom ntawm HPMC yog cov nyom ntau dua thiab muaj ntau yam.
2. Solubility thiab lub cev muaj zog
Solubility ntawm MC: Methylcellulose muaj solubility zoo hauv dej txias, tab sis tsis yaj nyob rau hauv dej kub. Nws txoj kev daws teeb meem yuav tsim cov gel qhov tshwm sim thaum ua kom sov, uas ua rau MC muaj tus yam ntxwv tshwj xeeb muaj nqis nyob rau qee yam kev mob tshwj xeeb, xws li nws cov ntawv thov hauv cov ntaub ntawv tsim tsev.
Solubility ntawm HPMC: Hauv kev sib piv, HPMC yog soluble nyob rau hauv ob qho tib si txias thiab dej kub, thiab nws cov kev daws teeb meem muaj qhov dav viscosity ntau. Tsis tas li ntawd, HPMC cov khoom pov thawj zoo nyob hauv cov kev daws teeb meem aqueous thiab tsis rhiab los hloov nyob rau hauv lub chaw tshuaj thiab khoom noj.
3. Cov chaw thov
Daim ntawv thov ntawm methylcellulose: vim yog cov khoom siv hluav taws xob thelal ntawm MC, feem ntau yog siv cov khoom noj khoom haus, thiab lwm yam. Hauv kev lag luam kws tshuaj, MC qee zaum siv los ua tus neeg sawv cev rau cov ntsiav tshuaj thiab cov duab ua yeeb yaj kiab rau cov ntsiav tshuaj.
Cov ntawv thov ntawm HydroxyPropyyl methylulose: HPMC muaj ntau yam ntau dua MC hauv ntau qhov kev lag luam vim nws dav dia solubility thiab ruaj khov. Piv txwv li, HPMC tau dav hauv kev lag luam kws tshuaj los npaj cov ntsiav tshuaj tso tawm thiab kuj yog cov tuab thiab roj nplua nyeem thiab roj nplua nyeem rau ophthalmic npaj. Hauv cov khoom siv tsim kho, HPMC feem ntau siv los ua cov tuab thiab dej-khaws cov neeg sawv cev rau cov neeg tuag, muab cov tshuaj nplaum. Ib qho ntxiv, HPMC kuj tseem siv los ua cov tuab dua, emulsifier thiab stabilizer nyob rau hauv kev lag luam khoom noj.
4. Kev ua haujlwm zoo thiab kev ua tau zoo sib txawv
Cov yam ntxwv ua haujlwm ntawm MC: Ib qho tshwj xeeb feature ntawm methylcellulose yog nws thermal gelling cov zog, uas ua rau nws muaj txiaj ntsig tshwj xeeb hauv cov ntawv thov thermal. Ib qho ntxiv, cov kua aqueous ntawm MC muaj qee qib ntawm pob tshab thiab cov haujlwm saum npoo av, uas tau txais txiaj ntsig hauv qee cov txheej txheem muaj kev muaj.
Cov yam ntxwv ua haujlwm ntawm HPMC: HydroxyPropyyl methylulose yog tus tswv yim los ntawm nws txoj kev txhawb nqa ntawm solubility thiab daws viscurity thiab zoo li nws cov ruaj khov rau qhov kub thiab txias thiab Ph. Cov yam ntxwv no ua HPMC nthuav qhia kev ua kom zoo thiab ruaj khov hauv ntau yam kev siv. Ib qho ntxiv, HPMC's Biocompatibility thiab tsis muaj tshuaj lom ua rau nws tseem ceeb tshwj xeeb hauv kev lag luam kho mob thiab khoom noj.
5. Kev tiv thaiv ib puag ncig thiab kev nyab xeeb
Cov yam ntxwv ib puag ncig ntawm MC thiab HPMC: raws li cellulose derivatives, MC thiab HPMC yog biodegradable cov ntaub ntawv thiab muaj tsawg dua rau ib puag ncig. Tsis tas li ntawd, ob yam khoom tsis muaj tshuaj lom, tsis muaj kev nyab xeeb thiab muaj kev nyab xeeb, ua rau lawv muaj kev sib cuag nrog cov khoom noj muaj txiaj ntsig thiab tshuaj.
Txawm hais tias methylcellulose (MC) thiab hydroxyprropyrescelulose (Hydmc) muaj cov yam ntxwv lub cev, cov yam ntxwv lub cev, cov yam ntxwv ntawm lub cev muaj qhov sib txawv vim qhov txawv txav. Muaj ntau yam sib txawv. Mc tsuas yog excrels rau hauv cov ntawv thov uas xav tau thermal gelling cov khoom, xws li hauv cov ntaub ntawv hauv tsev; Thaum HPMC tau siv dav hauv cov tshuaj, zaub mov thiab kev tsim cov lag luam vim nws qhov dav solubility, ruaj khov thiab tsis muaj tshuaj lom. Nkag siab txog qhov sib txawv ntawm ob tuaj yeem pab koj xaiv cov khoom kom tsim nyog rau cov ntawv thov tshwj xeeb.
Lub Sijhawm Post: Feb-17-2025