Hydroxyethyl cellulose (HEC) thiab Hydroxypropyl cellulose (HPC) yog ob qho tib si derivpose ntawm cellulose, lub ntuj polymer pom nyob hauv tsob ntoo cell phab ntsa. Cov derivatives no tau siv dav hauv ntau yam kev lag luam vim lawv cov khoom tshwj xeeb. Txawm hais tias lawv cov qauv siv tshuaj thiab cov qauv siv tshuaj lom neeg, muaj cov qauv tshuaj sib txawv ntawm HEC thiab HPC nyob rau hauv cov nqe lus ntawm lawv cov zog, kev siv, thiab siv.
Tus qauv tshuaj:
HEC thiab HPC yog ob qho tib si cellulose hloov kho nrog hydroxyalkyl pawg. Cov pab pawg no tau txuas nrog lub cellulose caj qaum dhau los ntawm ethere sib txuas, ua rau txhim kho solubility thiab lwm yam kev xav tau.
Hydroxyethyl cellulose (HEC):
Hauv HEC, cov pab pawg hydroxyethyl (-ch2ch2oh) tau txuas nrog cov khoom anhydoglulucose ntawm lub cellulose caj qaum.
Cov qib degree hloov pauv (DS) yog hais txog qhov nruab nrab ntawm cov neeg hydroxyethyl pawg ib pawg anhydroglulucose chav. Cov txiaj ntsig DS muaj txiaj ntsig tau qhia tau ntau dua qhov hloov chaw, ua rau muaj kev nce qib ntxiv thiab lwm yam kev hloov kho.
HydroxyPropyl cellulose (HPC):
Hauv HPC, cov pab pawg hydrox, -ch2chohch3) tau txuas nrog lub anhydroglules ntawm lub cellulose caj qaum.
Zoo ib yam li HEC, cov qib hloov pauv (DS) hauv HPC txiav txim siab nws cov khoom. Cov nuj nqis DS ntau dua ua rau muaj kev nce qib ua kom muaj zog thiab hloov kho cov khoom.
Lub cev lub cev:
HEC thiab HPC muaj lub cev zoo sib xws vim lawv cov pob cellulose cellulose. Txawm li cas los xij, hloov maj mam sib txawv tshwm sim los ntawm cov pab pawg alkyl uas txuas rau lub cellulose caj qaum.
Solubility:
Ob HEC thiab HPC yog soluble hauv dej thiab ntau yam kev daws teeb meem organic, nyob ntawm lawv cov degree hloov chaw. Cov nuj nqis muaj siab dua feem ntau ua rau muaj kev sib txuas zoo dua.
HEC nyhav rau kev nthuav tawm solubility hauv dej piv rau HPC, tshwj xeeb tshaj yog ntawm qis dua kub, vim yog cov pab pawg hydrophilic ntawm pawg neeg ua kom zoo.
Viscosity:
Tag nrho HEC thiab HPC muaj peev xwm tsim cov kev daws teeb meem thaum yaj hauv dej. Lub viscosity ntawm kev daws teeb meem nyob ntawm yam xws li polymer concentration, qib hloov chaw, thiab kub.
HPC cov kev daws teeb meem feem ntau yog viscosity ntau dua li HEC cov kev daws teeb meem ntawm cov pab pawg loj dua ntawm cov pab pawg ua haujlwm piv rau cov pab pawg neeg ua kom zoo.
Cov Ntawv Thov:
HEC thiab HPC pom ntau yam kev lag luam, suav nrog cov tshuaj, cov khoom lag luam, khoom noj, vim lawv cov khoom lag luam thiab versatility.
Kws Tshuaj:
Ob qho tib si HEC thiab HPC feem ntau siv ua cov tshuaj uas tau txais kev tshuaj hauv cov tshuaj ua haujlwm. Lawv pab ua cov neeg sawv cev ua kom tuab, cov yeeb yaj kiab, thiab viscosity modifiers hauv qhov ncauj, thiab ophthalmic formulations.
HPC, nrog nws cov viscosity thiab cov yeeb yaj kiab ua yeeb yaj kiab, feem ntau nyiam hauv kev siv cov tshuaj thiab qhov ncauj tsis sib haum.
Hec yog feem ntau siv hauv ophthalmic npaj vim nws zoo nkauj mucoadhesive cov khoom thiab sib xyaw nrog ocular cov ntaub so ntswg.
Cov khoom lag luam ntawm tus kheej:
Hauv cov tshuaj pleev ib ce thiab cov khoom saib xyuas tus kheej, ob qho tib si HEC thiab HPC tau siv raws li cov tshuaj zawv plaub hau, thiab cov yeeb yaj kiab, pleev xim, cream, thiab gels.
HEC tau nyiam nyob rau hauv cov khoom tu plaub hau vim nws cov khoom siv zoo heev thiab sib xyaw nrog ntau qhov surfactants.
HPC feem ntau siv hauv cov khoom tu kho mob, xws li tshuaj txhuam hniav thiab cov tshuaj yaug, vim nws cov cua sov thiab ua npuas dej.
Kev Lag Luam Khoom Noj:
HEC thiab HPC tau pom zoo cov zaub mov ntxiv nrog cov ntawv thov raws li cov tuab, stabilizers, thiab emulsifiers hauv cov khoom noj khoom haus.
Lawv feem ntau siv nyob rau hauv cov khoom noj mis nyuj, cov kua ntses, hnav khaub ncaws, thiab cov khoom qab zib los txhim kho kev ntxhib los mos, cov duab hau, thiab kev ruaj khov.
HEC feem ntau nyiam hauv cov khoom noj acidic vim nws txoj kev ruaj ntseg tshaj qhov dav dav.
Txheej txheem thiab cov khoom siv tsim khoom:
Hauv cov txheej txheem thiab cov khoom siv tsim kho, HEC thiab HPC tau siv ua cov neeg sawv cev ua kom tuab, cov tshuaj nplaum, cov khoom lag luam muaj suab paj nruag, thiab cov cementious formulations.
HEC tau nyiam nyob rau hauv looj cov xim pleev xim vim yog nws tus cwj pwm shear-thinning tus cwj pwm thiab compatibility nrog lwm cov xim ntxiv.
HPC feem ntau yog siv hauv cov khoom siv rau cov paj ntaub ntawv los txhim kho kev ua haujlwm, adhesion, thiab dej khaws cia.
Hydroxyethyl cellulose (HEC) thiab Hydroxypropyl cellulose (HPC) yog cellulose derivatives nrog cov khoom sib txawv thiab cov ntawv thov. Thaum ob leeg polymers qhia cov qauv tshuaj thiab cov khoom sib txawv, sib txawv tshwm sim los ntawm cov kab cellulose cellulose. Cov kev sib txawv no ua rau muaj kev sib txawv hauv kev hloov pauv hauv solubility, thiab kev ua tau zoo nyob rau ntau yam kev lag luam xws li cov tshuaj, khoom noj, khoom noj khoom haus, thiab cov khoom siv. Nkag siab cov kev sib txawv no yog qhov tseem ceeb rau kev xaiv cov cellulose tsim nyog rau cov ntawv thov tshwj xeeb, kom ua tau zoo thiab ua haujlwm.
Lub Sijhawm Post: Feb-18-2025