Cov tshuaj lom neeg ntawm HPMC hypromellose?

Hypromellose, tseem hu ua HydroxyPropyyl methylcellose (HPMC), yog hluavtaws polymer muab los ntawm cellulose. Nws yog dav siv nyob rau hauv cov tshuaj paus, kev lag luam thiab kev lag luam kom zoo li cov tuab tuabneeg ua tuab, emulsifier thiab binder. HPMC yog qhov tsis muaj tshuaj lom thiab biodegradable cov yeeb tshuaj, ua rau nws muaj kev nyab xeeb thiab ib puag ncig phooj ywg.

1. Dej Solubility

HPMC yog soluble hauv dej thiab ua kom meej meej lossis me ntsis opalescent daws. Lub solubility ntawm HPMC nyob ntawm nws qib viscosity, hnyav hnyav thiab qib hloov chaw. Viscosity ntau dua thiab cov qhab nia hnyav molecular muaj tsawg soluble dua cov qhab nia qis dua. Cov qib degree txiav txim siab txog cov naj npawb ntawm hydroxypropyl thiab methyl pawg txuas nrog HPMC cellulose caj qaum. Cov qib siab dua ntawm kev hloov chaw, qis dua cov dej solubility.

2. Tshuaj Txhuam Hniav

HPMC yog siv tshuaj tsis ruaj khov thiab tsis muaj kev cuam tshuam nrog feem ntau cov organic thiab inorganic tshuaj. Nws tiv taus alkalis, cov acids tsis muaj zog thiab feem ntau cov kuab tshuaj muaj kuab. Txawm li cas los xij, HPMC reacts nrog cov muaj zog acids muaj zog thiab oxidizing cov neeg sawv cev, ua rau nws cov kev ua kom tsis ncaj ncees thiab tsis ua haujlwm. Yog li ntawd, nws pom zoo kom tsis txhob muaj HPMC kom muaj zog acids lossis oxidizing cov neeg sawv cev.

3. Zaj duab xis-tsim cov khoom

HPMC muaj cov yeeb yaj kiab zoo tshaj plaws thiab haum rau cov ntsiav tshuaj txheej, txhawb nqa cov txheej txheej thiab encapsulation. Zaj duab xis tsim los ntawm HPMC yog hloov tau yooj yim, pob tshab thiab du. Cov yeeb yaj kiab kuj txwv tsis pub muaj kev mob ntawm cov khoom siv nquag hauv cov ntsiav tshuaj lossis tshuaj ntsiav.

4. Thermal gelation

Nyob ntawm nws cov qib viscosiae thermal gelation thaum rhuab hauv dej saum toj ib yam li kub. Qhov kub thiab txias li cas los ntawm 50 ° C rau 90 ° C. Cov gel tsim los ntawm HPMC yog reversible, lub ntsiab lus nws tuaj yeem tau melted rov qab mus rau lub xeev ua kua los ntawm kev txias. Cov cuab yeej no ua rau HPMC haum rau kev siv hauv kev tswj hwm-tso tawm, txij li thaum cov tshuaj tuaj yeem tso tawm ntawm qhov kub tshwj xeeb.

5. Rheological cov yam ntxwv

HPMC cov khoom ua pov thawj pseudopastic tus cwj pwm, lub ntsiab lus hais tias nws viscosity txo nrog nce shear tus nqi. Cov cuab yeej no ua rau HPMC haum rau siv raws li tuab thiab stabilizer nyob rau hauv cov zaub mov thiab cov tshuaj pleev ib yam. HPMC kuj tseem raug siv los ua tus cwj pwm tsis raug cai vim nws qhov kev coj cwj pwm thixotropic, uas txhais tau tias nws viscosity txo qis nroos kev ntxhov siab.

HPMC yog ib qho khoom siv thiab muaj kev nyab xeeb nrog cov tshuaj zoo heev. Nws cov dej solubility, tshuaj lom neeg ruaj khov, zaj duab xis ua yeeb yam, thermogigling thiab rheological cov khoom ua rau nws muaj kev lag luam nrov. HPMC kuj tseem biodegradable thiab ib puag ncig phooj ywg, ua rau nws xaiv lub suab.