HydroxyPropyylencellulose (HPMC) thiab nws cov derivatives, suav nrog methylcellulose (mc), thiab kev ua kom zoo rau lawv cov khoom siv hauv cov sib txawv, xws li Kws Tshuaj thiab khoom noj los tsim kho thiab kev saib xyuas tus kheej.
Cellulose derivatives yog qhov tseem ceeb hauv ntau kev lag luam vim lawv cov khoom siv ntau yam thiab cov ntawv thov. Ntawm cov derivatives, hydroxypropylencelulose (HPMC), Methylcellulose (HEC), thiab canc) sawv tawm rau lawv cov yam ntxwv siv dav dav thiab txawv.
1.qhemical qauv:
HydroxyPropyyl methylcellulose (HPMC):
HPMC yog synthesized los ntawm cellulose los ntawm kev hloov kho tshuaj lom neeg muaj feem nrog cov pab pawg hauv hydroxyl nrog methlox thiab hydroxypropropsyl pawg. Cov qib degree hloov pauv (DS) txiav txim siab nws cov khoom, suav nrog viscosity thiab solubility. HPMC cov tshuaj kho tshuaj uas cuam tshuam cov khoom ua yeeb yaj kiab zoo thiab cov dej sib dhos thiab dej kom haum rau ntau yam kev siv.
Methylcellulose (MC):
MC muab tau los ntawm cellulose los ntawm kev hloov cov pawg hydroxyl nrog methyl pawg. Tsis zoo li HPMC, Mc tsis muaj cov pab pawg hydroxypropylropyl. Nws cov khoom yog cuam tshuam los ntawm cov ntsiab lus xws li qib ntawm kev hloov pauv thiab hnyav hnyav. MC Cov Khoom Taw Qhia Zoo Ua Kom Zoo thiab thickening cov yam ntxwv, ua rau nws muaj txiaj ntsig zoo hauv kev lag luam zoo li cov tshuaj thiab khoom noj.
Hydroxyethyl cellulose (HEC):
HEC tau synthesized los ntawm etherification ntawm cellulose nrog ethylene oxide. Cov lus qhia ntawm cov pab pawg hydroxyethyl uas muaj cov khoom ntiag tug xws li high thicking efficiency thiab pseudoplasticity. HEC tau dav siv hauv cov khoom lag luam ntawm tus kheej, xim, thiab cov nplaum vim nws cov tshuaj lom neeg tswj thiab ua yeeb yaj kiab.
Carboxymethyl cellulose (CMC):
CMC yog tsim los ntawm rapacting cellulose nrog chloroacetic acid los yog nws cov ntsev ntsev. Cov pab pawg carboxymethyl tau qhia, txhim kho cov khoom ntiag tug xws li cov dej solubility, viscosity, thiab ruaj khov. CMC nrhiav cov ntawv thov hauv cov khoom noj, cov tshuaj, thiab roj roj vim nws cov thickening, ruaj khov, thiab cov khoom siv khi.
Nplooj ntawv:
Viscosity:
HPMC, MC, HEC, thiab CMC nthuav dav sib txawv cov viscosity theem nyob ntawm seb cov degecular hnyav, thiab hnyav. Feem ntau, HPMC thiab MC Muaj kev txhawb nqa viscosity malcority rau HEC thiab CMC, nrog HEC muab cov kev ua kom zoo dua ntawm cov qis dua.
Dej khaws cia:
HPMC thiab MC muaj lub peev xwm khiav ceev ceev, tseem ceeb rau cov kev siv uas yuav tsum muaj noo noo kev khaws thiab kev tso dej num ntev ntev. Hec tseem ua rau cov dej ua kom zoo, thaum cmc muaj dej xyaum ua kom muaj zog vim nws lub siab solubility.
Zaj duab xis tsim:
HPMC thiab HEC paub txog lawv cov yeeb yaj kiab-tsim lub peev xwm, ua kom muaj kev txhim kho ntawm kev sib koom ua ke thiab cov yeeb yaj kiab hloov tau. MC, txawm hais tias muaj peev xwm tsim cov yeeb yaj kiab, tuaj yeem nthuav tawm brittleness piv rau HPMC thiab HEC. CMC, feem ntau siv los ua lub thickening thiab ruaj khov, tau muaj kev ua yeeb yaj kiab ua yeeb yaj kiab.
Solubility:
Tag nrho plaub cellulose derivatives yog dej-soluble rau sib txawv. HPMC, MC, thiab CMC yaj yooj yim rau hauv dej, Thaum Hec Cov Khoom Taw Qhia Txo Solubility, uas xav tau qhov kub dua rau kev xaus. Ib qho ntxiv, cov qib ntawm cov hloov pauv cuam tshuam rau cov solubility ntawm cov derivatives no.
3.Aplpications:
Kws Tshuaj:
HPMC thiab MC yog qhov dav nyob rau hauv cov kws tshuaj tsim kho raws li cov neeg sawv cev, tsis sib haum xeeb, thiab tso tawm-tso tawm cov neeg sawv cev vim lawv cov biocompatibility thiab kev tso tawm cov khoom tso tawm. HEC pom cov ntawv thov hauv Ophthalmic daws teeb meem thiab cov qauv ntawm cov ncauj lus tawm mus rau nws txoj kev ntshiab thiab viscosity tswj. CMC tau ua haujlwm hauv qhov ncauj thiab cov ntsiav tshuaj rau nws cov kev cuam tshuam tuab thiab ruaj khov.
Kev Lag Luam Khoom Noj:
CMC ua si lub luag haujlwm tseem ceeb hauv kev ua lag luam khoom noj ua cov ntaub tuab, thiab muaj roj hloov cov khoom lag luam zoo li cov khoom noj mis nyuj khov, cov khoom noj qab zib, thiab cov khoom noj bakery. HPMC thiab MC tabtom siv hauv cov khoom noj khoom haus rau lawv cov tuab yaj ua kom tuab, thiab cov dej-khi dej. HEC tsis tshua muaj ntau tab sis tuaj yeem siv rau hauv cov ntawv thov tshwj xeeb xws li cov khoom noj muaj calorie tsawg thiab dej haus.
Kev Tsim Kho:
HPMC tau tshaj tawm hauv cov khoom tsim kho xws li cov khoom noj khoom haus zoo xws li cov khoom lag luam tsis sib xws, thiab cov khoom lag luam gypsum, thiab cov dej ua haujlwm, thiab cov khoom siv ua kom muaj txiaj ntsig. MC kuj tseem siv nyob rau hauv cov ntawv thov zoo sib xws, ua rau muaj kev txhim kho kev sib txawv thiab cohesion. HEC pom tsawg siv nyob rau hauv kev tsim kho vim nws tus nqi siab dua piv rau HPMC thiab MC.
Cov khoom lag luam ntawm tus kheej:
HEC thiab HPMC tau nthuav dav nyob rau hauv cov khoom tu tus kheej xws li tshuaj zawv plaub hau, muaj cov tshuaj pleev xim, thiab cov creaming, thiab cov yeeb yaj kiab. Lawv kev sib raug zoo nrog ntau yam tshuaj pleev ib ce thiab lawv lub peev xwm los txhim kho cov khoom lag luam tsim khoom ua rau lawv tsis tseem ceeb hauv cov qauv. CMC yuav siv tau hauv Niche cov ntawv thov nyob rau hauv kev lag luam saib xyuas kev saib xyuas vim nws cov khoom ruaj khov thiab thickening.
4.Ntustrial tseem ceeb:
Qhov tseem ceeb ntawm HPMC thiab nws cov kev dag ntxias nyob hauv lawv cov kev ua haujlwm ntau thiab hloov kho thoob plaws ntau yam lag luam. Cov cellulose derivatives ua haujlwm tseem ceeb hauv cov qauv, pab rau cov khoom lag luam zoo, ua haujlwm, thiab kev ua haujlwm. Lawv cov neeg sib txawv ua rau lawv tsis tseem ceeb hauv cov haujlwm xws li cov kws tshuaj, kev tsim kho, thiab kev saib xyuas tus kheej, tsav tsheb ua haujlwm tsim kho tshiab thiab kev loj hlob ua haujlwm tshiab thiab kev lag luam tshiab.
HydroxyPropyyl methylulose (HPMC) thiab nws cov derivcellulose, suav nrog methylcellulose (mc), muab cov khoom siv roj cellulechlulose (mc), muab cov khoom siv hluav taws xob (CLC) Thaum cov cellulose kev faib cov kev sib tw ntawm cov tshuaj lom neeg thiab cov khoom sib zog ntawm cov kabmob ntawm viscosity, dej ceev, thiab solubility. Nkag siab cov kev sib txawv no yog qhov tseem ceeb rau kev txhim kho lawv cov kev siv thoob plaws kev lag luam, txhawb kev muaj tswv yim tshiab, thiab tsav tsheb kev lag luam.
Lub Sijhawm Post: Feb-18-2025