Hydroxyethyl cellulose (HEC) yog siv cov polymer hauv ntau yam kev lag luam vim nws cov khoom lag luam xws li cov dej solubility, thickening muaj peev xwm, thiab biocompatibility. Nkag siab txog nws qhov kev ruaj khov nyob rau hauv hom hom sib txawv yog qhov tseem ceeb rau nws cov ntawv thov tau zoo.
Hydroxyethyl cellulose (HEC) yog ib qho kev sib tw ntawm cellulose, ib qho tshwm sim polymer muaj ntau yam nyob hauv cov phab ntsa ntawm tes. HEC tau txais txiaj ntsig zoo hauv kev lag luam xws li cov tshuaj yeeb, tshuaj pleev ib ce, thiab muaj peev xwm ua rau cov dej solubility, muaj peev xwm ua yeeb yam thickening, thiab biocompatibility. Txawm li cas los xij, qhov ruaj khov ntawm hac nyob rau hauv pH cov hom sib txawv yog qhov tseem ceeb rau nws daim ntawv thov tau zoo hauv ntau yam qauv.
Qhov ruaj khov ntawm HEC tuaj yeem cuam tshuam los ntawm ntau yam, nrog ph ua ib qho ntawm cov tsis tseem ceeb tshaj plaws. PH cuam tshuam rau ionization xeev ntawm cov pab pawg ua haujlwm tam sim no hauv HEC, yog li cuam tshuam nws solubility, viscosity, thiab lwm yam khoom. Nkag siab txog kev coj cwj pwm ntawm qhov chaw sib tw sib txawv yog qhov tseem ceeb rau cov kws sau ntawv los ua kom zoo rau nws cov kev ua tau zoo hauv ntau yam kev siv.
1.Qhov txheej txheem qauv ntawm hydroxyethyl cellulose:
HEC tau synthesized los ntawm cov tshuaj tiv thaiv ntawm ethylene oxide, ua rau kev qhia ntawm hydroxyethyl pawg mus rau lub cellulose capulose. Cov qib ntawm qhov hloov pauv (DS) ntawm pab pawg Hydroxyethyl txiav txim siab cov khoom ntawm HEC, suav nrog nws solubility thiab thickening muaj peev xwm. Cov qauv tshuaj kho mob ntawm HEC IM CARNARTS tshwj xeeb cov yam ntxwv uas ua rau nws haum rau ntau cov ntawv thov.
Lub Koom Haum Qeb Ua Haujlwm hauv Hec yog hydroxyl (-h) thiab ether (-h) thiab-) pawg, uas ua ib pawg neeg tseem ceeb hauv nws cov dej thiab lwm yam lwg me me. Qhove no ntawm hydroxyethyl chaw nce ntxiv cov cellrophilicity ntawm cellwb muaj kev txhim kho cov dej solubility piv rau cov cellulose haiv neeg. Cov etheres sib txuas muab kev ruaj khov rau HEC lwg me, tiv thaiv lawv qhov kev tsis zoo nyob rau hauv ib txwm muaj.
2.teraction nrog pH:
Qhov ruaj khov ntawm HEC hauv cov chaw sib tw sib txawv yog cuam tshuam los ntawm kev ionization ntawm nws pawg ua haujlwm. Hauv cov xwm txheej acidic (ph <7), cov pab pawg hydroxyl tam sim no hauv Hydrox tuaj yeem tawm suab, ua rau txo qis hauv solubility thiab viscosity. Conversely, hauv Alkaline tej yam kev mob (Ph> 7), tsis muaj sia ntawm hydroxyl pawg yuav tshwm sim, cuam tshuam rau cov khoom polymer cov khoom.
Ntawm qhov qes ph, kev tawm ntawm cov pab pawg hydroxyl tuaj yeem cuam tshuam nrog kev sib txuas lus hauv polymer lifix, ua kom txo cov solubility thiab thickening efficiency. Qhov tshwm sim no muaj ntau dua nyob rau theem siab dua ntawm kev hloov chaw, qhov twg ntau dua ntawm cov pab pawg hydroxyl muaj rau cov tswv cuab. Raws li qhov tshwm sim, cov tshuaj tua kab mob hec yuav txo qis hauv cov acidic ib puag ncig, cuam tshuam nws qhov kev ua tau zoo li tus neeg saib xyuas tuab.
Ntawm qhov tod tes, hauv cov xwm txheej alkaline, deproonation ntawm hydroxyl pawg tuaj yeem nce cov solubility ntawm hec vim qhov tsim ntawm alkoxide ions. Txawm li cas los xij, ntau dhau Alkalinity tuaj yeem ua rau kev mob siab ntawm cov polymer los ntawm cov hydrolysis ntawm ob leeg sib txuas, ua rau muaj kev txo qis hauv viscosity thiab lwm yam khoom. Yog li ntawd, tswj cov pH nyob rau hauv ib qho kev haum yog qhov tseem ceeb kom ntseeg tau tias qhov kev ruaj ntseg ntawm hac hauv cov qauv alkaline.
3.Cractical cuam tshuam:
Qhov kev ruaj ntseg ntawm HEC hauv ntau qhov chaw pH muaj cov kev ua tau zoo cuam tshuam cuam tshuam rau nws cov kev siv hauv ntau hom kev lag luam. Hauv kev lag luam kws tshuaj, HEC feem ntau ua haujlwm raws li tus neeg saib xyuas thicking hauv cov qauv qauv xws li kev ncua, emulsions, thiab gels. PHIC ntawm cov qauv no yuav tsum ua tib zoo tswj kom muaj qhov xav tau viscosity thiab ruaj khov ntawm Hec.
Ib yam li ntawd, hauv kev lag luam tshuaj pleev ib yam nkaus, HEC tau siv hauv cov khoom xws li tshuaj zawv plaub hau xws li tshuaj zawv plaub hau, creams, thiab tshuaj rau nws cov cua sov thiab emulsifying rau nws cov khoom siv. PHIC ntawm cov qauv no tuaj yeem sib txawv ntawm cov khoom lag luam tshwj xeeb nyob ntawm cov khoom lag luam tshwj xeeb thiab qhov sib xyaw ntawm HEC nrog lwm cov khoom xyaw. Cov kws sau yuav tsum xav txog qhov cuam tshuam ntawm PH ntawm kev ruaj ntseg thiab kev ua tau zoo ntawm HEC kom ntseeg tau cov khoom muaj txiaj ntsig thiab cov neeg siv khoom txaus siab.
Hauv kev lag luam khoom noj khoom haus, HEC yog siv ua lub thickening thiab ruaj khov hauv ntau yam khoom, suav nrog cov kua ntses, hnav khaub ncaws, thiab cov khoom qab zib. PHOO cov khoom noj muaj peev xwm ntau yam los ntawm acidic rau alkaline rau alkaline, nyob ntawm cov khoom xyaw thiab kev ua. Nkag siab txog kev coj cwj pwm yog qhov tseem ceeb rau kev ua tiav cov kev xav tau, cov ncauj lus, thiab kev ruaj khov hauv cov khoom noj.
Hauv kev tsim kho kev tsim kho, HEC tau ua haujlwm hauv cov ntawv thov xws li cov kev cai tsa suab paj nruag, groutions, thiab cov nplaum rau nws cov dej tswj thiab kev tswj hwm kev tswj hwm. PHIC ntawm cov qauv no tuaj yeem sib txawv raws li cov xwm txheej xws li kev kho mob thiab muaj cov ntxiv. Ua kom zoo rau PE ruaj khov ntawm hac yog qhov tseem ceeb rau kev ua kom muaj kev ua tau zoo thiab ua kom cov khoom siv tsim kho.
Qhov ruaj khov ntawm hydroxyethyl cellulose (HEC) nyob rau hauv ntau qhov chaw kuaj ntshav, kev sib cuam tshuam nrog pH, thiab cov tswv yim cuam tshuam hauv kev lag luam sib txawv. Nkag siab txog kev coj cwj pwm ntawm HEC nyob rau hauv cov hom Phem sib txawv yog qhov tseem ceeb rau cov ua kom zoo ua kom nws cov kev ua tau zoo hauv kev siv ntau yam. Cov kev tshawb fawb ntxiv yog qhov xav tau rau eluceting lub pib tswj kev ruaj ntseg ntawm HEC thiab txhim kho cov tswv yim los txhim kho nws cov kev ua tau zoo nyob hauv hom kab sib txawv.
Lub Sijhawm Post: Feb-18-2025