HydroxyPropyyl methylcellose (HPMC) yog siv cov polymer dav nrog ntau yam kev siv hauv tshuaj, khoom noj khoom haus, tshuaj pleev ib ce thiab kev tsim kho. Cov lus nug ntawm hydrophilicity thiab lipophilicity ntawm HPMC feem ntau yog nyob ntawm nws cov qauv tshuaj thiab cov molecular.
Tshuaj lom neeg cov qauv thiab cov khoom ntawm HPMC
HPMC yog qhov tsis-ionic cellulose derivative tsim los ntawm kev qhia txog hydroxypropyl thiab methyl pawg rau hauv cov qauv molecular. Nws cov molecular saw muaj hydrophilic hydroxyl (-h) thiab lipophilic methyl (-ch3) thiab hydroxypropyl (-ch2ch (Oh) CH3) pawg. Yog li ntawd, nws muaj ob tug tswv yim, ob leeg hydrophilic thiab lipophilic, tab sis lub hydrophilicity yog me ntsis tseem ceeb. Cov cuab yeej no muab nws zoo solubility, ua yeeb yaj kiab ua yeeb yaj kiab thiab thickening cov khoom tawg, thiab tuaj yeem tsim ruaj khov colloidal dispersion thiab cov kuab tshuaj organic.
Hydrophilicity ntawm HPMC
Vim yog cov pab pawg hydroxyl hauv HOLMC qauv, nws cov molecular saw muaj muaj zog hydrophilicity. Hauv dej, HPMC tuaj yeem tsim cov lwg me me, tso cai rau cov molecules kom yaj hauv dej thiab ua qhov kev daws teeb meem siab. Tsis tas li ntawd, HPMC kuj muaj dej ua ke zoo thiab tau siv dav ua cov tuab thiab khov kho hauv tshuaj, khoom noj thiab cov tshuaj pleev ib ce thiab cov tshuaj pleev ib ce thiab cov tshuaj pleev ib ce. Piv txwv li, HPMC tuaj yeem siv ua tus neeg sawv cev-tso tawm hauv kev npaj tshuaj hauv lub cev thiab txhim kho kev ruaj ntseg ntawm kev ua tau tshuaj.
Lipophilicity ntawm HPMC
Cov methyl thiab hydroxypropropyl hauv Hydrophobicity muaj qee qhov Liplophobicity, yog li HPMC kuj muaj qee qhov polvents los ua cov tshuaj ruaj khov. Nws lipophilicity ua rau nws sib xyaw nrog qee cov roj cov tshuaj, uas ua kom cov roj siv tau ntawm HPMC hauv-dej (O / W) emulsxes thiab hmab. Hauv qee qhov emulsions lossis compound npaj, lub lipophilicity ntawm hydrophobic tshuaj, yog li ua kom tau faib tawm thiab ruaj khov ntawm cov khoom xyaw.
Daim ntawv thov HPMC
Kws npaj tshuaj: HPMC feem ntau siv los ua cov khoom siv hluav taws xob hauv cov ntsiav tshuaj, siv nws cov khoom siv hydrophilicity thiab cov yeeb yaj kiab-ua yeeb yaj kiab los tswj cov tshuaj tso tawm Yeeb Tshuaj.
Kev lag luam khoom noj khoom haus: hauv zaub mov, HPMC yog siv los ua cov tuab thiab dej rov qab los txuas ntxiv lub txee lub neej thiab txhim kho qhov saj.
Cov ntaub ntawv tsim tsev: HPMC cov dej solubility thiab thillening cov nyhuv ua rau nws txoj kev cai cug ua kom huv hauv kev tsim kho, txhim kho cov haujlwm ua haujlwm thiab dej muaj peev xwm tuav cov khoom.
Cov tshuaj pleev ib ce: Hauv cov khoom saib xyuas tawv nqaij, HPMC tuaj yeem siv ua emulsifier stabilizer. Vim nws hydrophilicity, nws tuaj yeem tsim ib lub aqueous Matrix los tswj cov nyhuv ya raws thiab kev ntxhib los mos ntawm cov khoom.
HPMC yog cov khoom siv amphipilic polymer uas yog ydrophilic thiab lipophilic, tab sis vim tias nws muaj ntau pab pawg hydroxylicity.
Lub sijhawm Post: Feb-15-2025