Taw qhia rau HPMC:
HydroxyPropyyl methylcellose (HPMC) yog lub cellulose derivative nrog kev siv hauv ntau yam kev lag luam, kev tsim kho, thiab tshuaj pleev noj, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce. Nws yog feem ntau siv los ua cov tuab dua, emiulsifier, thiab zaj duab xis yav dhau los rau nws cov khoom, suav nrog cov dej solubility, ua yeeb yaj kiab ua yeeb yam, thiab viscosity.
Qhov tseem ceeb ntawm kev faib ua kom tiav:
Kev ua kom zoo ntawm HPMC hauv dej yog qhov tseem ceeb heev kom ua tiav qhov kev ua haujlwm tau xav tau thiab ua haujlwm. Kev rho tawm tsis txaus tuaj yeem ua rau cov teeb meem xws li clumping, tsis sib luag, lossis kev ua haujlwm tsis zoo ntawm cov khoom kawg. Yog li ntawd, nws yog qhov tseem ceeb kom ua raws cov tswv yim tshwj xeeb los xyuas kom ntseeg tau tias muaj kev sib cais tshwj xeeb.
Cov cuab yeej siv thiab cov khoom siv xav tau:
HydroxyPropyyl Methylcellulose (HPMC)
Distilled dej (lossis dej deionized)
Nws cov thawv ntim khoom (iav lossis yas)
Stirring pas nrig lossis cov khoom siv neeg tshuab
Ntsuas ntsuas lossis tawv
Tus pas ntsuas kub (xaiv tau, rau cov ntawv thov kub-rhiab)
Cov kauj ruam ib theem zuj zus:
1. Npaj:
Xyuas kom meej tias txhua yam khoom siv thiab cov khoom siv yog huv thiab pub dawb los ntawm tej yam tsis huv. Siv dej distilled lossis deistized los tiv thaiv cov impurities uas yuav cuam tshuam rau cov txheej txheem kev hloov pauv.
2. Ntsuas cov dej:
Ntsuas cov dej uas tsim nyog rau koj cov qauv. Qhov ntau ntawm cov dej nyob ntawm qhov xav tau kev xav ntawm HPMC thiab qhov kawg ntim ntawm kev daws. Siv lub tog raj kheej kawm tiav lossis ntsuas lub khob rau kev ntsuas yog qhov tseeb.
3. Maj mam ntxiv HPMC:
Pib maj mam ntxiv HPMC hmoov rau cov dej thaum nplawm tsis tu ncua. Nws yog qhov tseem ceeb ntxiv cov hmoov maj mam tiv thaiv clumping thiab paub tseeb tias muaj kev sib txawv ntawm cov lus.
4. Agitation:
Txuas ntxiv nplawm qhov sib xyaw kom haum rau kev rho tawm ntawm HPMC hais hauv dej. Siv cov pas nrig stirring rau cov ntawv thov me me lossis cov khoom siv neeg kho tshuab rau cov khoom loj dua. Xyuas kom meej tias lub stirring action yog txaus kom tawg cov agglomerates thiab ua tiav homogeneous dispersion.
5. Hydration:
Cia HPMC hais rau hydrate tag nrho hauv dej. Cock yog cov kauj ruam tseem ceeb uas ua rau cov saw polymer rau swell thiab yaj, tsim cov tshuaj pleev. Nyob ntawm cov qhab nia ntawm HPMC thiab qhov xav tau viscosity, hydration yuav siv sijhawm ob peb feeb txog ob peb teev. Xa mus rau cov chaw tsim khoom cov txheej txheem rau kev pom zoo hydration lub sij hawm.
6. Kev tswj kub (yeem):
Rau cov ntawv thov kub-rhiab, xws li cov tshuaj lossis khoom noj khoom haus, saib xyuas qhov kub ntawm cov dispersion. Zam kev kub ntau dhau, raws li nws yuav ua rau HPMC lossis cuam tshuam cov khoom ntawm cov khoom kawg. Yog tias tsim nyog, siv dej da dej lossis qhov chaw khiav kub thiab kub kom muaj kev tswj hwm kom muaj qhov kub thiab txias thaum lub sijhawm rho tawm.
7. Kho PH (yog tias xav tau):
Hauv qee qhov tsim qauv, kho cov dej hauv yuav tsim nyog los ua kom zoo rau kev dispersion ntawm HPMC. Tham cov khoom lag luam lossis cov lus qhia tsim qauv los txiav txim siab txog cov qauv PHEMIM LI CAS rau koj daim ntawv thov. Siv cov kua qaub lossis alkali daws teeb meem los kho cov pH raws li kev xav tau, thiab txuas ntxiv stirring kom txog rau thaum cov Phe xav tau ua tiav.
8. PaClele loj txo (yeem):
Yog tias HPMC cov lus tseem ceeb tshaj plaws lossis yog qhov tsis tshua muaj txiaj ntsig rau koj daim ntawv thov, xav txog cov tswv yim ntxiv los txo cov particle. Cov hau kev xws li milling, homogenization, lossis ultrasonication tuaj yeem pab rhuav tshem agglomerates thiab txhim kho dispersion. Txawm li cas los xij, ceev faj kom tsis txhob ua kom dhau cov txheej txheem dispersion, raws li ntau heev shear yuav dhuav cov polymer.
9. Kuaj thiab Tswj Tswjhwm Zoo:
Tom qab cov txheej txheem dispersion tiav, ua kev tswj hwm zoo kom ntseeg tau cov yam ntxwv xav tau ntawm HPMC daws. Ntsuas tsis xws li viscosity, pH, clarity, thiab particle loj faib kom paub qhov zoo ntawm cov dispersion. Kho cov qauv tsim lossis kev ua haujlwm raws li xav tau kom tau raws li cov kev xav tau.
10. Cia thiab tuav:
Khaws lub HPMC dispersion nyob rau hauv cov thawv uas tsim nyog los tiv thaiv kev paug thiab evaporation. Foob cov ntim kom nruj kom tswj tau qhov zoo ntawm kev daws teeb meem dhau sijhawm. Ua raws li cov neeg mob kom pom zoo, suav nrog cov kev pab kub thiab cov av noo, kom ntev rau lub neej sib luag ntawm cov dispersion.
11. Kev ceev faj kev nyab xeeb:
Kov HPMC thiab cov kev daws teeb meem dej nrog kev saib xyuas kom tsis txhob muaj tawv nqaij, qhov muag, lossis nqus tau. Hnav cov khoom tiv thaiv tus kheej tsim nyog, xws li hnab looj tes thiab kev tiv thaiv kev nyab xeeb, thaum ua haujlwm nrog cov tshuaj. Ua raws li cov lus qhia kev nyab xeeb thiab cov cai tshwj xeeb rau koj kev lag luam lossis daim ntawv thov.
Dispersing HPMC nyob rau hauv dej yog ib qib tseem ceeb hauv ntau cov txheej txheem muaj, suav nrog cov tshuaj, kev tsim kho, thiab tshuaj pleev noj, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce, thiab tshuaj pleev noj, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce, thiab tshuaj pleev noj, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce, thiab tshuaj pleev noj, thiab tshuaj pleev ib ce, thiab tshuaj pleev ib ce, thiab cov tshuaj pleev ib ce. Los ntawm cov tswv yim zoo thiab cov txheej txheem ua tiav, koj tuaj yeem ua tiav cov kev sib cais ntawm HPMC hais, kom ua tau zoo thiab ua haujlwm hauv cov khoom kawg. Ua tib zoo saib cov sijhawm thiab lub sijhawm tswj qhov kub, thiab tswj qhov ntsuas kub, thiab tswj kom zoo rau HPMC cov kev siv HPMC zoo.
Lub Sijhawm Post: Feb-18-2025