HPMC (HydroxyPropyyl methylcellulose) yog ib txwm siv polymer siv nyob rau hauv kev npaj cov ntsiav tshuaj, qhov muag poob thiab lwm yam khoom. Nws lub sijhawm sib cais yog nyob ntawm ntau yam, suav nrog molecular hnyav, daws qhov kub, nplawm kev nrawm thiab siab.
1. Molecular hnyav thiab qib hloov chaw
Qhov hnyav molecular thiab qib degree hloov chaw (piv txwv li, metoxy thiab hydroxypropyls) ntawm HMMC yuav cuam tshuam nws solubility. Feem ntau hais lus, tus loj dua cov molecular hnyav, ntev nws yuav siv kom yaj. Tsawg viscosity HPMC (qis molecular hnyav) feem ntau yuav siv 20-40 feeb kom yaj txog kev kub siab (thaum siab molecular hnyav) yuav siv sijhawm ntau teev kom yaj tag.
2. Tshuaj Kub
Qhov ntsuas kub ntawm kev daws teeb meem muaj qhov cuam tshuam tseem ceeb ntawm kev sib cais ntawm HPMC. Cov txheej txheem kub siab dua feem ntau ua rau cov txheej txheem sib cais, tab sis kub uas siab dhau yuav ua rau muaj kev cuam tshuam ntawm HPMC. Feem ntau cov kev sib hais txog qhov kub yog nyob nruab nrab ntawm 20 ° C thiab 60 ° C, thiab cov kev xaiv tshwj xeeb yog nyob ntawm tus yam ntxwv ntawm HPMC thiab lub hom phiaj ntawm kev siv.
3. Stirring ceev
Nplawm tuaj yeem txhawb kev sib cais ntawm HPMC. Tsim kom zoo tuaj yeem tiv thaiv cov agglomeration thiab nag lossis daus ntawm HPMC thiab ua kom tusyees impersed hauv kev daws. Kev xaiv ntawm stirring ceev yuav tsum tau hloov kho raws li cov khoom siv tshwj xeeb thiab cov yam ntxwv ntawm HPMC. Feem ntau, txaus siab cov txiaj ntsig tuaj yeem ua tiav los ntawm kev nplawm rau 20-40 feeb.
4. Kev daws teeb meem
Cov concentration ntawm HPMC tseem yog qhov tseem ceeb ntawm kev txiav txim siab nws lub sijhawm sib cais. Qhov siab dua ntawm lub sij hawm, ntev dua lub sijhawm kawg nkaus xwb. Rau kev tsis tshua muaj siab (<2% w / w) HPMC lub sijhawm yuav luv dua, thaum ntau dua cov kev daws teeb meem xav tau sijhawm ntxiv kom yaj.
5. Kev Xaiv Cov Mob
Ntxiv rau dej, HPMC kuj tseem tuaj yeem yaj nyob rau lwm cov kuab tshuaj xws li Ethanol thiab ethylene glycol. Cov polarity thiab solubility ntawm cov kuab tshuaj sib txawv yuav cuam tshuam rau kev sib cais ntawm HPMC thiab cov yam ntxwv ntawm kev daws zaum kawg.
6. Preprocessing txoj kev
Qee txoj kev pretreaticment, xws li ua ntej ntub hpmc lossis siv dej kub, tuaj yeem pab ua kom nws cov txheej txheem sib cais. Tsis tas li ntawd, kev siv ntawm kev tawm ntawm cov kev pab cuam xws li surfactants kuj tseem tuaj yeem txhim kho kev ua haujlwm ua tiav kev ua haujlwm sib txawv.
Lub sijhawm ua tiav ntawm HPMC cuam tshuam los ntawm ntau yam. Yog li ntawd, hauv cov ntawv thov siv, cov xwm txheej sib nrauj yuav tsum tau hloov kho raws li cov kev cai siv tshwj xeeb siv thiab cov yam ntxwv ntawm HPMC. Feem ntau, lub sijhawm yuav tsum tau HPMC kom yaj nyob rau hauv cov neeg tsim nyog muaj txij li 30 feeb txog ob peb teev. Rau cov khoom lag luam HPMC thiab cov ntawv thov thov kom xa mus rau cov lus qhia cov khoom lag luam lossis kev sim ua kom paub txog kev ua kom pom kev zoo tshaj plaws thiab sijhawm.
Lub Sijhawm Post: Feb-17-2025