HydroxyPropyyl methylcellueculose (HPMC) yog qhov tsis muaj ionic, dej-soluble cellulose feem ntau li cov chaw ua tshuaj, khoom noj, tshuaj pleev zaub mov, thiab kev tsim kho. Ib qho ntawm nws cov cwj pwm tseem ceeb yog nws lub peev xwm los muab viscosity zoo ib txwm nyob hauv kev daws teeb meem thiab cov qauv. Cov txheej txheem tom qab HPMC muaj peev xwm tswj tau ruaj khov thiab muaj peev xwm to taub los ntawm kev tshuaj xyuas nws cov qauv molecular, thiab kev coj cwj pwm nyob rau hauv cov xwm txheej sib txawv.
Molecular qauv thiab solubility
HPMC yog muab tau los ntawm cellulose, lub ntuj polymer muaj cov roj hazos uas txuas nrog los ntawm β-1,4-glycosidic bonds. Cov txheej txheem hloov kho cuam tshuam nrog cov kev qhia methoxy thiab hydroxypropey, uas ua rau hydroxypropylagylulose. Qhov kev hloov pauv no tau txhim kho rau solubility ntawm HPMC hauv dej thiab cov kuab tshuaj organic.
Cov qib degree hloov pauv (DS) thiab cov hniav puas hloov (MS) yog qhov tsis tshua muaj kev txhais HPMC cov khoom siv. DS hais txog cov pawg nruab nrab ntawm cov pawg hydroxyl hloov ib pawg ntawm cov moles ntawm mole ntawm anhydogluent. Cov teeb tsa no cuam tshuam HPMC's Solubility, thermal khoom, thiab viscosity.
Cov Cuab Nruab Nruab Nruab Nrab ntawm Viscosity muaj zog
Cock thiab gel tsim:
Thaum HPMC ntxiv rau dej, nws undergoes rydration, uas dej lwg me thiab cuam tshuam nrog cov saw polymer, ua rau lawv o. Cov txheej txheem kev lag luam cov roj kas no ua rau tsim cov gel network uas ua rau muaj kev daws teeb meem. Cov hydration yog cuam tshuam los ntawm qhov kub, pH, thiab muaj cov ntsev, tab sis HPMC cov qauv molecular tso cai rau nws ua ib qho chaw nyob ruaj khov thoob plaws ntau yam.
Molecular hnyav thiab polymer saw sib cuam tshuam:
Qhov hnyav molecular ntawm HPMC cuam tshuam loj cuam tshuam nws viscosity. Ntau dua molecular phaus polymers muaj cov saw ntev ntev, uas entangle yooj yim dua, nce cov tshuaj viscosity. HPMC muaj nyob rau hauv ntau qib nrog hnyav molecular hnyav, tso cai meej tswj hwm lub viscosity ntawm cov khoom kawg. Kev ua haujlwm tau txais thiab kev sib cuam tshuam ntawm cov saw hlau polymer tsim lub network uas muab viscosity zoo sib xws.
Thermal gelation:
HPMC cov khoom pov thawj tshwj xeeb cov cua sov gelation cov khoom, qhov twg nws ua cov gel raws li cov cua sov thiab kub ua rau kev daws thaum txias. Qhov kev thim rov qab no yog vim yog cov methoxy thiab hydroxyprropyl pawg ntawm kev sib cuam tshuam hydrophobic ntawm cov chaw kub, coj mus rau gel tsim. Thaum txias txias, cov kev sib cuam tshuam no diminish, thiab gel yaj. Cov cuab yeej no yog siv tau tshwj xeeb hauv cov ntawv thov uas xav tau hloov chaw thaum muaj kev tswj xyuas tag nrho.
Rheological tus cwj pwm:
HPMC cov kev daws teeb meem Tsis yog-Newtonian, shear-thij-them, lub ntsiab lus lawv viscosity txo nrog nce shear tus nqi. Cov cuab yeej no kom ntseeg tau tias nyob rau hauv kev sib tw sib xyaw ua ke, cov tshuaj tua kab mob HPMC tau hloov kho kom haum tab sis rov qab mus rau nws lub xeev shear raug tshem tawm. Qhov kev coj cwj pwm thixotropic no pab tswj cov viscosity raws li lub sijhawm thov.
Pho stability:
Tsis zoo li ntau lwm cov neeg polymers, HPMC yog qhov tsis txaus siab rau qhov ntau ntawm 3 txog 11. Raws li qhov tshwm sim, HPMC tswj cov viscosity nyob thoob plaws, ua rau nws haum rau ntau yam kev siv ps qhov twg yuav hloov pauv.
Cov ntawv thov tau txais txiaj ntsig los ntawm cov viscosity zoo ib yam
Kws Tshuaj
Hauv cov yeeb yaj kiab kws tshuaj, HPMC yog siv los ua cov tuab, tuav, thiab tswj-tso tawm tus neeg sawv cev. Nws cov viscosity zoo li yog qhov tseem ceeb rau kev faib cov tshuaj uas muaj kev faib tawm, raug tshem tawm tsis yooj yim, thiab kev tawm yeeb tshuaj uas tau hais tawm uas tau tso tawm. Piv txwv li, hauv cov ntsiav tshuaj ntsiav tshuaj, HPMC ua kom du, txawm tias siv cov kev daws teeb meem uas tsim nyog, nws muab cov kev tsim nyog siv rau lub qhov muag.
Kev Lag Luam Khoom Noj
Hauv kev lag luam khoom noj, HPMC ua raws li emulsifier, stabilizer, thiab tuab. Nws lub peev xwm los muab viscosity raws nraim yog qhov tseem ceeb rau kev tswj cov kev ntxhib los mos thiab cov khoom lag luam zoo li cov kua ntses, cov khoom hnav, thiab cov khoom noj ua haus. HPMC cov khoom siv thermal gelation yog tshwj xeeb yog muaj txiaj ntsig hauv cov khoom lag luam uas yuav tsum tau hloov chaw thaum ua noj.
Kev tsa tsev
Hauv kev tsim kho cov khoom siv, HPMC yog siv hauv cov cement thiab plaster cov qauv tsim los txhim kho cov haujlwm hauv kev ua haujlwm, kev ua kom dej, thiab cov nplaum. Cov ntsiab lus viscosity zoo ib yam kom cov ntaub ntawv no tuaj yeem thov kom zoo thiab tswj lawv txoj kev ncaj ncees thaum lub sij hawm kho.
Tshuaj pleev ib ce
HPMC tau ua haujlwm hauv cov tshuaj pleev ib ce rau nws cov cua sov thiab ruaj khov. Hauv cov khoom lag luam xws li muaj cov tshuaj pleev, cream, thiab tshuaj zawv plaub hau, thiab viscosity ua kom muaj kev paub zoo thiab ruaj khov, txhim kho cov neeg siv kev paub.
Yam cuam tshuam rau viscosity thiab tswj hwm zoo
Ntau yam muaj peev xwm cuam tshuam cov kev daws teeb meem ntawm HPMC, suav nrog kev xav, thiab yog muaj cov electrolytes lossis lwm yam ntxiv. Yuav kom ua tiav qhov viscosity, nws yog qhov tseem ceeb kom tswj cov kab no thaum lub sijhawm tsim thiab ua. Kev tswj kom zoo xws li:
Xaiv cov khoom siv Raw:
Ua kom muaj kev siv cov cellule high-purity cellulose thiab tswj kev hloov pauv ntawm kev hloov pauv ntawm kev hloov HPMC nrog cov khoom muaj peev xwm txhim khu kev qha.
Cov txheej txheem raug:
Tswj cov txheej txheem tsim kho, nrog rau kev tswj hwm pom ntawm cov kev tiv thaiv thaum lub sijhawm ua haujlwm Hetheric nrog lub cev hnyav thiab cov qauv hloov pauv.
Kev Ntsuam Xyuas Kev Ntsuam Xyuas:
Kev ntsuas kev ntsuas ib txwm ntawm HPMC Batches rau viscosity, kev faib nyiaj hnyav, thiab cov qauv hloov chaw pab kom cov khoom lag luam kom ua kom cov khoom lag luam. Cov tswv yim xws li viscometry, gel permication stratography, thiab nuclear sib nqus resonance spectroscopy feem ntau siv.
Cia thiab tuav:
Kev khaws cia zoo thiab tuav ntawm HPMC kom tiv thaiv noo noo mus thiab kev txwv tsis tseem ceeb. HPMC yuav tsum tau muab khaws cia rau hauv cov thawv airtight thiab hauv qhov txias, mob kom tswj tau nws cov khoom.
HPMC lub peev xwm los muab viscosity zoo sib xws los ntawm nws cov qauv molecular, cov khoom lag luam ntawm hydration, thiab kev coj ua thermal gelation, thiab thermal gelation tus cwj pwm. Nws cov ruaj khov hla PHAW PHIC theem, thiab ua kom muaj kev ua tau zoo nyob rau hauv ntau yam kev mob polymer hauv ntau kev lag luam. Los ntawm kev ceev faj cov txheej txheem ntawm cov txheej txheem ntau lawm thiab kev tsim kho zoo HPMC ua kom tau raws li cov kev xav tau ntawm txoj hlua khi.
Lub Sijhawm Post: Feb-18-2025