HPMC (HydroxyPropyyl methylcellulose) yog cov multifunctional polymer composed dav siv hauv cov tshuaj, khoom noj khoom haus thiab kev lag luam. Nws yog tsim los ntawm cov tshuaj hloov kho lub cev hloov kho thiab muaj cov dej solubility zoo thiab kev ruaj khov. Raws li rau seb HPMC tuaj yeem yaj nyob hauv dej kub, nws yuav tsum tau tshuaj xyuas los ntawm kev sib raug zoo ntawm nws cov xeeb ceem thiab dej kub.
1. Cov yam ntxwv ntawm HPMC
HPMC yog cov dej nonionic-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose-soluble cellulose eteas tuaj yeem ua rau cov dej txias thiab tsim cov pa taws. Nws cov solubility yog cuam tshuam ntau dua los ntawm qhov kub thiab txias, uas yog feem ntau cuam tshuam hauv cov hauv qab no:
Tsawg qis kub solubility: hauv dej txias (feem ntau yog qis dua 40 ° yuav sai tau nqus dej thiab swell, maj mam yaj ua ib qho kev daws teeb meem.
Cov dej kub Dispersility: HPMC yog insoluble hauv dej siab, tab sis tuaj yeem raug xa tawm los ua ib qho kev ncua. Thaum cov dej txias rau qhov ntsuas kub, cov lus tau pib yaj.
2. Kev Txwv ntawm kev sib cais hauv dej kub
Kev ua tau zoo ntawm HPMC hauv dej kub yog qhov ze rau qhov kub thiab txias:
Tsis yog ncaj qha soluble hauv dej kub: nyob rau hauv kub (feem ntau tshaj 60 ° C) ib puag ncig yuav plam solubility thiab ua ib qho qauv network. Qhov tshwm sim no hu ua "thermal gelation", uas yog, HPMC molecules sib sau ua ke hauv dej kub los ntawm kev sib koom tes hydrogen khi.
Haum cov qauv daws: Ntxiv HPMC mus rau dej kub thiab do kom huv si los ua ib qho ruaj khov. Raws li cov tee ntsuas kub, lub thermal gelation tshwm sim, thiab cov lus yuav nqus dej dua thiab maj mam yaj.
3. Cov kev tshem tawm hauv cov ntawv thov siv
Txhawm rau txhim kho kev sib cais ntawm HPMC thiab kev sib txawv ntawm kev daws teeb meem, cov hauv qab no feem ntau siv:
Cov dej kub thiab txias sib xyaw: ua ntej HPMC rau dej kub txog li 70 ° C kom tsis txhob stirring agglomeration, thiab tom qab ntawd txuas ntxiv cov txheej txheem thaum nws yaj tag.
Hmoov qhuav Pre-dispersion txheej: sib xyaw HPMC nrog lwm cov hmoov av yooj yim (xws li cov hmoov nplej qhuav), uas tuaj yeem nce cov kev sib cais.
4. Kev ceev faj
Zam kev kub ntxhov heev: HPMC yuav plam solubility saum nws gelation kub (feem ntau ntawm 60-75 ° C).
Do kom zoo: Nco ntsoov cov nplais tau zoo tawg thaum ntxiv dej los tiv thaiv kom tiv thaiv qhov tsim ntawm cov lumrule insoluble.
HPMC tsis yog soluble nyob rau hauv dej kub, tab sis tuaj yeem raug tawg nyob rau hauv dej kub los ua ib qho kev ncua, uas yuav yaj tom qab txias. Yog li ntawd, txoj kev ua kom yog yog qhov tseem ceeb rau nws cov hauj lwm zoo. Hauv cov ntawv thov, cov xwm txheej sib nrauj yuav tsum tau hloov kho raws li cov kev xav tau kom muab tag nrho cov kev ua si rau nws cov thickening, ruaj khov los yog zaj duab xis-ua cov khoom.
Lub sijhawm Post: Feb-15-2025